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Drug holiday in patients with polycystic liver disease treated with somatostatin analogues
BACKGROUND: Somatostatin analogues (SAs) reduce liver volume and relief symptoms in polycystic liver disease (PLD). Its effect wears off after continuing therapy suggesting development of SA tolerance in patients on chronic therapy. We postulate that a drug holiday resensitizes the liver to its acut...
Autores principales: | van Aerts, René M. M., Kolkman, Marieke, Kievit, Wietske, Gevers, Tom J. G., Nevens, Frederik, Drenth, Joost P. H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6172936/ https://www.ncbi.nlm.nih.gov/pubmed/30302127 http://dx.doi.org/10.1177/1756284818804784 |
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