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Antiphospholipid Antibodies to Domain I of Beta-2-Glycoprotein I Show Different Subclass Predominance in Comparison to Antibodies to Whole Beta-2-glycoprotein I
Antiphospholipid antibodies (aPL), the serological hallmark of antiphospholipid syndrome (APS), are a heterogeneous group of autoantibodies raised against circulating blood proteins. Of these proteins, the phospholipid-binding b2-glycoprotein I (β2GPI) is considered to be the main autoantigen in APS...
Autores principales: | McDonnell, Thomas, Artim-Esen, Bahar, Wincup, Chris, Ripoll, Vera M., Isenberg, David, Giles, Ian P., Rahman, Anisur, Pericleous, Charis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173128/ https://www.ncbi.nlm.nih.gov/pubmed/30323817 http://dx.doi.org/10.3389/fimmu.2018.02244 |
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