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Multicolor single particle reconstruction of protein complexes

Single-particle reconstruction (SPR) from electron microscopy images is widely used in structural biology, but lacks direct information on protein identity. To address this limitation, we developed a computational and analytical framework that reconstructs and co-aligns multiple proteins from 2D sup...

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Detalles Bibliográficos
Autores principales: Sieben, Christian, Banterle, Niccolò, Douglass, Kyle M., Gönczy, Pierre, Manley, Suliana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173288/
https://www.ncbi.nlm.nih.gov/pubmed/30275574
http://dx.doi.org/10.1038/s41592-018-0140-x