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Multicolor single particle reconstruction of protein complexes
Single-particle reconstruction (SPR) from electron microscopy images is widely used in structural biology, but lacks direct information on protein identity. To address this limitation, we developed a computational and analytical framework that reconstructs and co-aligns multiple proteins from 2D sup...
Autores principales: | Sieben, Christian, Banterle, Niccolò, Douglass, Kyle M., Gönczy, Pierre, Manley, Suliana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173288/ https://www.ncbi.nlm.nih.gov/pubmed/30275574 http://dx.doi.org/10.1038/s41592-018-0140-x |
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