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Elucidating the novel BRCA1 function as a non-genomic metabolic restraint in ER-positive breast cancer cell lines

Within populations carrying the same genetic predisposition, the penetrance of BRCA1 mutations has increased over time. Although linked to changes in lifestyle factors associated with energy metabolism, these observations cannot be explained by the established role of BRCA1 in DNA repair alone. We m...

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Detalles Bibliográficos
Autores principales:	Koobotse, Moses, Holly, Jeff, Perks, Claire
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173354/ https://www.ncbi.nlm.nih.gov/pubmed/30323899 http://dx.doi.org/10.18632/oncotarget.26093

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