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The Akt/mTOR pathway in cancer stem/progenitor cells is a potential therapeutic target for glioblastoma and neuroblastoma

Nervous system tumors represent some of the highly aggressive cancers in both children and adults, particularly neuroblastoma and glioblastoma. Many studies focused on the pathogenic role of the Akt pathway and the mechanistic target of Rapamycin (mTOR) complex in mediating the progression of variou...

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Detalles Bibliográficos
Autores principales: Bahmad, Hisham F., Mouhieddine, Tarek H., Chalhoub, Reda M., Assi, Sahar, Araji, Tarek, Chamaa, Farah, Itani, Muhieddine M., Nokkari, Amaly, Kobeissy, Firas, Daoud, Georges, Abou-Kheir, Wassim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173359/
https://www.ncbi.nlm.nih.gov/pubmed/30323898
http://dx.doi.org/10.18632/oncotarget.26088