Compound C inhibits nonsense-mediated RNA decay independently of AMPK

The nonsense mediated RNA decay (NMD) pathway safeguards the integrity of the transcriptome by targeting mRNAs with premature translation termination codons (PTCs) for degradation. It also regulates gene expression by degrading a large number of non-mutant RNAs (including mRNAs and noncoding RNAs) t...

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Detalles Bibliográficos
Autores principales: Cheruiyot, Abigael, Li, Shan, Nickless, Andrew, Roth, Robyn, Fitzpatrick, James A. J., You, Zhongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173407/
https://www.ncbi.nlm.nih.gov/pubmed/30289931
http://dx.doi.org/10.1371/journal.pone.0204978

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