Cargando…

Aminoglycoside-inducible expression of the mexAB-oprM multidrug efflux operon in Pseudomonas aeruginosa: Involvement of the envelope stress-responsive AmgRS two-component system

Exposure of P. aeruginosa to the aminoglycoside (AG) paromomycin (PAR) induced expression of the PA3720-armR locus and the mexAB-oprM multidrug efflux operon that AmgR controls, although PAR induction of mexAB-oprM was independent of armR. Multiple AGs promoted mexAB-oprM expression and this was los...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fruci, Michael, Poole, Keith
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173428/ https://www.ncbi.nlm.nih.gov/pubmed/30289929 http://dx.doi.org/10.1371/journal.pone.0205036

Ejemplares similares

Pentachlorophenol Induction of the Pseudomonas aeruginosa mexAB-oprM Efflux Operon: Involvement of Repressors NalC and MexR and the Antirepressor ArmR
por: Starr, Lisa M., et al.
Publicado: (2012)

Dynamics of Intact MexAB-OprM Efflux Pump: Focusing on the MexA-OprM Interface
por: López, Cesar A., et al.
Publicado: (2017)

AmgRS-mediated envelope stress-inducible expression of the mexXY multidrug efflux operon of Pseudomonas aeruginosa
por: Lau, Calvin Ho-Fung, et al.
Publicado: (2015)

MexAB-OprM Efflux Pump Interaction with the Peptidoglycan of Escherichia coli and Pseudomonas aeruginosa
por: Ma, Miao, et al.
Publicado: (2021)

Molecular rationale for the impairment of the MexAB-OprM efflux pump by a single mutation in MexA
por: Cacciotto, Pierpaolo, et al.
Publicado: (2021)

Interplay between MexAB-OprM and MexEF-OprN in clinical isolates of Pseudomonas aeruginosa
por: Horna, Gertrudis, et al.
Publicado: (2018)

MexAB-OprM Efflux Pump of Pseudomonas aeruginosa Offers Resistance to Carvacrol: A Herbal Antimicrobial Agent
por: Pesingi, Prasanna Vadhana, et al.
Publicado: (2019)

Structures of the wild-type MexAB–OprM tripartite pump reveal its complex formation and drug efflux mechanism
por: Tsutsumi, Kenta, et al.
Publicado: (2019)

Premature Termination of MexR Leads to Overexpression of MexAB-OprM Efflux Pump in Pseudomonas aeruginosa in a Tertiary Referral Hospital in India
por: Choudhury, Debarati, et al.
Publicado: (2016)

Characterization of a MexAB-OprM efflux system necessary for productive metabolism of Pseudomonas azelaica HBP1 on 2-hydroxybiphenyl
por: Czechowska, K., et al.
Publicado: (2013)

Correction: Premature Termination of MexR Leads to Overexpression of MexAB-OprM Efflux Pump in Pseudomonas aeruginosa in a Tertiary Referral Hospital in India
por: Choudhury, Debarati, et al.
Publicado: (2016)

Role of Two Sets of RND-Type Multidrug Efflux Pump Transporter Genes, mexAB-oprM and mexEF-oprN, in Virulence of Pseudomonas syringae pv. tabaci 6605
por: Ichinose, Yuki, et al.
Publicado: (2020)

132. Evaluation Phage Cocktails in Combination with Ciprofloxacin Against Multidrug-Resistant Pseudomonas aeruginosa Overexpressing MexAB-OprM Efflux Systems
por: Holger, Dana, et al.
Publicado: (2021)

Nucleotide substitutions in the mexR, nalC and nalD regulator genes of the MexAB-OprM efflux pump are maintained in Pseudomonas aeruginosa genetic lineages
por: Aguilar-Rodea, Pamela, et al.
Publicado: (2022)

Transcriptional Analysis of MexAB-OprM Efflux Pumps System of Pseudomonas aeruginosa and Its Role in Carbapenem Resistance in a Tertiary Referral Hospital in India
por: Choudhury, Debarati, et al.
Publicado: (2015)

The antimicrobial peptide Esc(1-21)-1c increases susceptibility of Pseudomonas aeruginosa to conventional antibiotics by decreasing the expression of the MexAB-OprM efflux pump
por: Canè, Carolina, et al.
Publicado: (2023)

RND type efflux pump system MexAB-OprM of pseudomonas aeruginosa selects bacterial languages, 3-oxo-acyl-homoserine lactones, for cell-to-cell communication
por: Minagawa, Shu, et al.
Publicado: (2012)

CpxR Activates MexAB-OprM Efflux Pump Expression and Enhances Antibiotic Resistance in Both Laboratory and Clinical nalB-Type Isolates of Pseudomonas aeruginosa
por: Tian, Zhe-Xian, et al.
Publicado: (2016)

In vitro Investigation of the MexAB Efflux Pump From Pseudomonas aeruginosa
por: Verchère, Alice, et al.
Publicado: (2014)

siRNA-mediated gene silencing of MexB from the MexA-MexB-OprM efflux pump in Pseudomonas aeruginosa
por: Gong, Feng-Yun, et al.
Publicado: (2014)

Investigation of aminoglycoside resistance inducing conditions and a putative AmrAB-OprM efflux system in Burkholderia vietnamiensis
por: Jassem, Agatha N, et al.
Publicado: (2014)

Antibiotic export by MexB multidrug efflux transporter is allosterically controlled by a MexA-OprM chaperone-like complex
por: Glavier, Marie, et al.
Publicado: (2020)

Expression of the MexXY-OprM efflux system in Pseudomonas aeruginosa with discordant cefepime/ceftazidime susceptibility profiles
por: Laohavaleeson, Somvadee, et al.
Publicado: (2008)

Di-berberine conjugates as chemical probes of Pseudomonas aeruginosa MexXY-OprM efflux function and inhibition
por: Kavanaugh, Logan G., et al.
Publicado: (2023)

Mutations in nalc gene of Mex AB-OprM efflux pump in carbapenem resistant Pseudomonas aeruginosa isolated from burn wounds in Yazd, Iran
por: Tafti, Fatemeh Akhavan, et al.
Publicado: (2020)

Efflux MexAB-Mediated Resistance in P. aeruginosa Isolated from Patients with Healthcare Associated Infections
por: Kishk, Rania M., et al.
Publicado: (2020)

Catch me if you can: a biotinylated proteoliposome affinity assay for the investigation of assembly of the MexA-MexB-OprM efflux pump from Pseudomonas aeruginosa
por: Ntsogo Enguéné, Véronique Yvette, et al.
Publicado: (2015)

Berberine Derivatives as Pseudomonas aeruginosa MexXY-OprM Inhibitors: Activity and In Silico Insights
por: Giorgini, Giorgia, et al.
Publicado: (2021)

Efflux-mediated fluoroquinolone resistance in the multidrug-resistant Pseudomonas aeruginosa clinical isolate PA7: identification of a novel MexS variant involved in upregulation of the mexEF-oprN multidrug efflux operon
por: Morita, Yuji, et al.
Publicado: (2015)

Focus on the Outer Membrane Factor OprM, the Forgotten Player from Efflux Pumps Assemblies
por: Phan, Gilles, et al.
Publicado: (2015)

Antibiotic Inducibility of the mexXY Multidrug Efflux Operon of Pseudomonas aeruginosa: Involvement of the MexZ Anti-Repressor ArmZ
por: Hay, Thomas, et al.
Publicado: (2013)

Evidence of MexT-Independent Overexpression of MexEF-OprN Multidrug Efflux Pump of Pseudomonas aeruginosa in Presence of Metabolic Stress
por: Kumar, Ayush, et al.
Publicado: (2011)

Crystal Structure of the Regulatory Domain of MexT, a Transcriptional Activator of the MexEF-OprN Efflux Pump in Pseudomonas aeruginosa
por: Kim, Suhyeon, et al.
Publicado: (2019)

Role of the Multidrug Resistance Efflux Pump MexCD-OprJ in the Pseudomonas aeruginosa Quorum Sensing Response
por: Alcalde-Rico, Manuel, et al.
Publicado: (2018)

New OprM structure highlighting the nature of the N-terminal anchor
por: Monlezun, Laura, et al.
Publicado: (2015)

Expression of the MexXY Aminoglycoside Efflux Pump and Presence of an Aminoglycoside-Modifying Enzyme in Clinical Pseudomonas aeruginosa Isolates Are Highly Correlated
por: Seupt, Alexander, et al.
Publicado: (2020)

Involvement of MexS and MexEF-OprN in Resistance to Toxic Ion Chelators in Pseudomonas putida KT2440
por: Henriquez, Tania, et al.
Publicado: (2020)

MexEF-OprN Efflux Pump Exports the Pseudomonas Quinolone Signal (PQS) Precursor HHQ (4-hydroxy-2-heptylquinoline)
por: Lamarche, Martin G., et al.
Publicado: (2011)

MexY-Promoted Aminoglycoside Resistance in Pseudomonas aeruginosa: Involvement of a Putative Proximal Binding Pocket in Aminoglycoside Recognition
por: Lau, Calvin Ho-Fung, et al.
Publicado: (2014)

Berberine Is a Novel Type Efflux Inhibitor Which Attenuates the MexXY-Mediated Aminoglycoside Resistance in Pseudomonas aeruginosa
por: Morita, Yuji, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_fddokms4v2nmlppctu283h4m7d