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The trypanocidal benzoxaborole AN7973 inhibits trypanosome mRNA processing
Kinetoplastid parasites—trypanosomes and leishmanias—infect millions of humans and cause economically devastating diseases of livestock, and the few existing drugs have serious deficiencies. Benzoxaborole-based compounds are very promising potential novel anti-trypanosomal therapies, with candidates...
Autores principales: | Begolo, Daniela, Vincent, Isabel M., Giordani, Federica, Pöhner, Ina, Witty, Michael J., Rowan, Timothy G., Bengaly, Zakaria, Gillingwater, Kirsten, Freund, Yvonne, Wade, Rebecca C., Barrett, Michael P., Clayton, Christine |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173450/ https://www.ncbi.nlm.nih.gov/pubmed/30252911 http://dx.doi.org/10.1371/journal.ppat.1007315 |
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