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Nuclear PKM2 promotes the progression of oral squamous cell carcinoma by inducing EMT and post-translationally repressing TGIF2

Pyruvate kinase M2 (PKM2), a glycolytic enzyme, acts as a metabolic function leading to an energy production critical for cancer progression, known as Warburg effect. In this study we showed a pivotal role of PKM2 acting as a non-metabolic function to promote cancer cell progression in human oral sq...

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Detalles Bibliográficos
Autores principales:	Tanaka, Fumie, Yoshimoto, Shohei, Okamura, Kazuhiko, Ikebe, Tetsuro, Hashimoto, Shuichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173467/ https://www.ncbi.nlm.nih.gov/pubmed/30333907 http://dx.doi.org/10.18632/oncotarget.25850

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