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The close relationship between heparanase and epithelial mesenchymal transition in gastric signet-ring cell adenocarcinoma

Heparanase (HPSE), a heparan sulfate-specific endo-β-D-glucuronidase, plays an important role in tumor cell metastasis through the degradation of extracellular matrix heparan sulfate proteoglycans. Suramin, a polysulfonated naphthylurea, is an inhibitor of HPSE with suramin analogues. Our objective...

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Detalles Bibliográficos
Autores principales:	Shah, Shahid, Fourgeaud, Caroline, Derieux, Simon, Mirshahi, Shahsoltan, Contant, Geneviève, Pimpie, Cynthia, Lo Dico, Rea, Soria, Jeannette, Pocard, Marc, Mirshahi, Massoud
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2018
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173471/ https://www.ncbi.nlm.nih.gov/pubmed/30333909 http://dx.doi.org/10.18632/oncotarget.26042

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