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Biological Evaluation and Docking Studies of Synthetic Oleanane-type Triterpenoids
[Image: see text] Saponins are potential wide-spectrum antitumor drugs, and copper(I) catalyzed azide–alkyne 1,3-dipolar cycloaddition is a suitable approach to synthesizing saponin-like compounds by regioselective glycosylation of the C2/C3 hydroxyl and C28 carboxylic groups of triterpene aglycones...
Autores principales: | Ortega-Muñoz, Mariano, Rodríguez-Serrano, Fernando, De los Reyes-Berbel, Eduardo, Mut-Salud, Nuria, Hernández-Mateo, Fernando, Rodríguez-López, Andrea, Garrido, José M., López-Jaramillo, F. Javier, Santoyo-González, Francisco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173505/ https://www.ncbi.nlm.nih.gov/pubmed/30320262 http://dx.doi.org/10.1021/acsomega.8b01034 |
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