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Concerted IL-25R and IL-4Rα signaling drive innate type 2 effector immunity for optimal helminth expulsion

Interleukin 25 (IL-25) is a major 'alarmin' cytokine, capable of initiating and amplifying the type immune response to helminth parasites. However, its role in the later effector phase of clearing chronic infection remains unclear. The helminth Heligmosomoides polygyrus establishes long-te...

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Detalles Bibliográficos
Autores principales:	Smith, Katherine A, Löser, Stephan, Varyani, Fumi, Harcus, Yvonne, McSorley, Henry J, McKenzie, Andrew NJ, Maizels, Rick M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2018
Materias:	Immunology and Inflammation
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173579/ https://www.ncbi.nlm.nih.gov/pubmed/30238872 http://dx.doi.org/10.7554/eLife.38269

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