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Current approaches for modulation of the nanoscale interface in the regulation of cell behavior

Regulation of cell behavior in response to nanoscale features has been the focus of much research in recent years and the successful generation of nanoscale features capable of mimicking the natural nanoscale interface has been of great interest in the field of biomaterials research. In this review,...

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Detalles Bibliográficos
Autores principales: Donnelly, Hannah, Dalby, Matthew J, Salmeron-Sanchez, Manuel, Sweeten, Paula E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173683/
https://www.ncbi.nlm.nih.gov/pubmed/28552647
http://dx.doi.org/10.1016/j.nano.2017.03.020
Descripción
Sumario:Regulation of cell behavior in response to nanoscale features has been the focus of much research in recent years and the successful generation of nanoscale features capable of mimicking the natural nanoscale interface has been of great interest in the field of biomaterials research. In this review, we discuss relevant nanofabrication techniques and how they are combined with bioengineering applications to mimic the natural extracellular matrix (ECM) and create valuable nanoscale interfaces.