Suppressor mutations in Rpf2–Rrs1 or Rpl5 bypass the Cgr1 function for pre-ribosomal 5S RNP-rotation

During eukaryotic 60S biogenesis, the 5S RNP requires a large rotational movement to achieve its mature position. Cryo-EM of the Rix1-Rea1 pre-60S particle has revealed the post-rotation stage, in which a gently undulating α-helix corresponding to Cgr1 becomes wedged between Rsa4 and the relocated 5...

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Detalles Bibliográficos
Autores principales: Thoms, Matthias, Mitterer, Valentin, Kater, Lukas, Falquet, Laurent, Beckmann, Roland, Kressler, Dieter, Hurt, Ed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173701/
https://www.ncbi.nlm.nih.gov/pubmed/30291245
http://dx.doi.org/10.1038/s41467-018-06660-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173701/
https://www.ncbi.nlm.nih.gov/pubmed/30291245
http://dx.doi.org/10.1038/s41467-018-06660-w

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