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Determination of ED50 and time to effectiveness for intrathecal hydromorphone in laboring patients using Dixon’s up-and-down sequential allocation method

BACKGROUND: With the increasing occurrence of drug shortages, understanding the pharmacokinetics of alternative intrathecal opioid administration has gained importance. In particular, additional data are needed to comprehensively evaluate the analgesic properties of intrathecal hydromorphone in the...

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Detalles Bibliográficos
Autores principales:	O’Reilly-Shah, Vikas, Lynde, Grant C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173834/ https://www.ncbi.nlm.nih.gov/pubmed/30290794 http://dx.doi.org/10.1186/s12871-018-0603-8

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