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Transcriptional profiling of embryos lacking the lipoprotein receptor SR-B1 reveals a regulatory circuit governing a neurodevelopmental or metabolic decision during neural tube closure

BACKGROUND: The high-density lipoprotein receptor SR-B1 mediates cellular uptake of several lipid species, including cholesterol and vitamin E. During early mouse development, SR-B1 is located in the maternal-fetal interface, where it facilitates vitamin E transport towards the embryo. Consequently,...

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Detalles Bibliográficos
Autores principales: Santander, Nicolás, Lizama, Carlos, Murgas, Leandro, Contreras, Sebastián, Martin, Alberto J. M., Molina, Paz, Quiroz, Alonso, Rivera, Katherine, Salas-Pérez, Francisca, Godoy, Alejandro, Rigotti, Attilio, Busso, Dolores
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173885/
https://www.ncbi.nlm.nih.gov/pubmed/30290792
http://dx.doi.org/10.1186/s12864-018-5110-2