Acidic microenvironment plays a key role in human melanoma progression through a sustained exosome mediated transfer of clinically relevant metastatic molecules

BACKGROUND: Microenvironment cues involved in melanoma progression are largely unknown. Melanoma is highly influenced in its aggressive phenotype by the changes it determinates in its microenvironment, such as pH decrease, in turn influencing cancer cell invasiveness, progression and tissue remodell...

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Detalles Bibliográficos
Autores principales: Boussadia, Zaira, Lamberti, Jessica, Mattei, Fabrizio, Pizzi, Elisabetta, Puglisi, Rossella, Zanetti, Cristiana, Pasquini, Luca, Fratini, Federica, Fantozzi, Luca, Felicetti, Federica, Fecchi, Katia, Raggi, Carla, Sanchez, Massimo, D’Atri, Stefania, Carè, Alessandra, Sargiacomo, Massimo, Parolini, Isabella
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173926/
https://www.ncbi.nlm.nih.gov/pubmed/30290833
http://dx.doi.org/10.1186/s13046-018-0915-z

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