Glucocorticoid-induced CREB activation and myostatin expression in C2C12 myotubes involves phosphodiesterase-3/4 signaling

Muscle atrophy in metabolic conditions like chronic kidney disease (CKD) and diabetes are associated with glucocorticoid production, dysfunctional insulin/Akt/FoxO3 signaling and increased myostatin expression. We recently found that CREB, a transcription factor proposed to regulate myostatin expres...

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Detalles Bibliográficos
Autores principales: Xie, Yang, Perry, Ben D., Espinoza, Daniel, Zhang, Peng, Price, S. Russ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173943/
https://www.ncbi.nlm.nih.gov/pubmed/30025893
http://dx.doi.org/10.1016/j.bbrc.2018.07.056

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173943/
https://www.ncbi.nlm.nih.gov/pubmed/30025893
http://dx.doi.org/10.1016/j.bbrc.2018.07.056

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