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Reconsideration of sample size and power calculation for overall survival in cancer clinical trials
When designing a cancer clinical trial, it is usual to assume an exponential distribution for a time-to-event outcome such as overall survival (OS). OS is often expressed as the sum of progression-free survival (PFS) and survival post-progression (SPP), each of which is assumed to be exponentially d...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174257/ https://www.ncbi.nlm.nih.gov/pubmed/30302417 http://dx.doi.org/10.1016/j.conctc.2018.09.007 |