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Evaluation of Atrial Electromechanical Delay to Predict Atrial Fibrillation in Hemodialysis Patients

Background and objective: Prevalence of atrial fibrillation is higher in hemodialysis patients as compared to the general population. Atrial electromechanical delay is known as a significant predictor of atrial fibrillation. In this study, we aimed to reveal the relationship between atrial electrome...

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Autores principales: Gunes, Hakan, Sokmen, Abdullah, Kaya, Hakki, Gungor, Ozkan, Kerkutluoglu, Murat, Guzel, Fatma Betul, Sokmen, Gulizar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174336/
https://www.ncbi.nlm.nih.gov/pubmed/30344289
http://dx.doi.org/10.3390/medicina54040058
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author Gunes, Hakan
Sokmen, Abdullah
Kaya, Hakki
Gungor, Ozkan
Kerkutluoglu, Murat
Guzel, Fatma Betul
Sokmen, Gulizar
author_facet Gunes, Hakan
Sokmen, Abdullah
Kaya, Hakki
Gungor, Ozkan
Kerkutluoglu, Murat
Guzel, Fatma Betul
Sokmen, Gulizar
author_sort Gunes, Hakan
collection PubMed
description Background and objective: Prevalence of atrial fibrillation is higher in hemodialysis patients as compared to the general population. Atrial electromechanical delay is known as a significant predictor of atrial fibrillation. In this study, we aimed to reveal the relationship between atrial electromechanical delay and attacks of atrial fibrillation. Materials and methods: The study included 77 hemodialysis patients over 18 years of age giving written consent to participate in the study. The patients were divided into two groups based on the results of 24-h Holter Electrocardiogram (Holter ECG) as the ones having attacks of atrial fibrillation and the others without any attack of atrial fibrillation. Standard echocardiographic measurements were taken from all patients. Additionally, atrial conduction times were measured by tissue Doppler technique and atrial electromechanical delays were calculated. Results: Intra- and interatrial electromechanical delay were found as significantly lengthened in the group of patients with attacks of atrial fibrillation (p = 0.03 and p < 0.001 respectively). The optimal cut-off time for interatrial electromechanical delay to predict atrial fibrillation was >21 ms with a specificity of 79.3% and a sensitivity of 73.7% (area under the curve 0.820; 95% confidence interval (CI), 0.716–0.898). In the multivariate logistic regression model, interatrial electromechanical delay (odds ratio = 1.230; 95% CI, 1.104–1.370; p < 0.001) and hypertension (odds ratio = 4.525; 95% CI, 1.042–19.651; p = 0.044) were also associated with atrial fibrillation after adjustment for variables found to be statistically significant in univariate analysis and correlated with interatrial electromechanical delay. Conclusions: Interatrial electromechanical delay is independently related with the attacks of atrial fibrillation detected on Holter ECG records in hemodialysis patients.
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spelling pubmed-61743362018-10-18 Evaluation of Atrial Electromechanical Delay to Predict Atrial Fibrillation in Hemodialysis Patients Gunes, Hakan Sokmen, Abdullah Kaya, Hakki Gungor, Ozkan Kerkutluoglu, Murat Guzel, Fatma Betul Sokmen, Gulizar Medicina (Kaunas) Article Background and objective: Prevalence of atrial fibrillation is higher in hemodialysis patients as compared to the general population. Atrial electromechanical delay is known as a significant predictor of atrial fibrillation. In this study, we aimed to reveal the relationship between atrial electromechanical delay and attacks of atrial fibrillation. Materials and methods: The study included 77 hemodialysis patients over 18 years of age giving written consent to participate in the study. The patients were divided into two groups based on the results of 24-h Holter Electrocardiogram (Holter ECG) as the ones having attacks of atrial fibrillation and the others without any attack of atrial fibrillation. Standard echocardiographic measurements were taken from all patients. Additionally, atrial conduction times were measured by tissue Doppler technique and atrial electromechanical delays were calculated. Results: Intra- and interatrial electromechanical delay were found as significantly lengthened in the group of patients with attacks of atrial fibrillation (p = 0.03 and p < 0.001 respectively). The optimal cut-off time for interatrial electromechanical delay to predict atrial fibrillation was >21 ms with a specificity of 79.3% and a sensitivity of 73.7% (area under the curve 0.820; 95% confidence interval (CI), 0.716–0.898). In the multivariate logistic regression model, interatrial electromechanical delay (odds ratio = 1.230; 95% CI, 1.104–1.370; p < 0.001) and hypertension (odds ratio = 4.525; 95% CI, 1.042–19.651; p = 0.044) were also associated with atrial fibrillation after adjustment for variables found to be statistically significant in univariate analysis and correlated with interatrial electromechanical delay. Conclusions: Interatrial electromechanical delay is independently related with the attacks of atrial fibrillation detected on Holter ECG records in hemodialysis patients. MDPI 2018-08-25 /pmc/articles/PMC6174336/ /pubmed/30344289 http://dx.doi.org/10.3390/medicina54040058 Text en © 2018 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Gunes, Hakan
Sokmen, Abdullah
Kaya, Hakki
Gungor, Ozkan
Kerkutluoglu, Murat
Guzel, Fatma Betul
Sokmen, Gulizar
Evaluation of Atrial Electromechanical Delay to Predict Atrial Fibrillation in Hemodialysis Patients
title Evaluation of Atrial Electromechanical Delay to Predict Atrial Fibrillation in Hemodialysis Patients
title_full Evaluation of Atrial Electromechanical Delay to Predict Atrial Fibrillation in Hemodialysis Patients
title_fullStr Evaluation of Atrial Electromechanical Delay to Predict Atrial Fibrillation in Hemodialysis Patients
title_full_unstemmed Evaluation of Atrial Electromechanical Delay to Predict Atrial Fibrillation in Hemodialysis Patients
title_short Evaluation of Atrial Electromechanical Delay to Predict Atrial Fibrillation in Hemodialysis Patients
title_sort evaluation of atrial electromechanical delay to predict atrial fibrillation in hemodialysis patients
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174336/
https://www.ncbi.nlm.nih.gov/pubmed/30344289
http://dx.doi.org/10.3390/medicina54040058
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