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Pseudomonas aeruginosa infection increases the readmission rate of COPD patients

INTRODUCTION: Acute exacerbation of COPD (AECOPD) leads to rapid deterioration of pulmonary function and quality of life. It is unclear whether the prognosis for AECOPD differs depending on the bacterium or virus identified. The purpose of this study is to determine whether readmission of patients w...

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Autores principales: Choi, Juwhan, Oh, Jee Youn, Lee, Young Seok, Hur, Gyu Young, Lee, Sung Yong, Shim, Jae Jeong, Kang, Kyung Ho, Min, Kyung Hoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174684/
https://www.ncbi.nlm.nih.gov/pubmed/30323578
http://dx.doi.org/10.2147/COPD.S173759
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author Choi, Juwhan
Oh, Jee Youn
Lee, Young Seok
Hur, Gyu Young
Lee, Sung Yong
Shim, Jae Jeong
Kang, Kyung Ho
Min, Kyung Hoon
author_facet Choi, Juwhan
Oh, Jee Youn
Lee, Young Seok
Hur, Gyu Young
Lee, Sung Yong
Shim, Jae Jeong
Kang, Kyung Ho
Min, Kyung Hoon
author_sort Choi, Juwhan
collection PubMed
description INTRODUCTION: Acute exacerbation of COPD (AECOPD) leads to rapid deterioration of pulmonary function and quality of life. It is unclear whether the prognosis for AECOPD differs depending on the bacterium or virus identified. The purpose of this study is to determine whether readmission of patients with severe AECOPD varies according to the bacterium or virus identified. METHODS: We performed a retrospective review of medical records of 704 severe AECOPD events at Korea University Guro Hospital from January 2011 to May 2017. We divided events into two groups, one in which patients were readmitted within 30 days after discharge and the other in which there was no readmission. RESULTS: Of the 704 events, 65 were followed by readmission within 30 days. Before propensity score matching, the readmission group showed a higher rate of bacterial identification with no viral identification and a higher rate of identification with the Pseudomonas aeruginosa (P=0.003 and P=0.007, respectively). Using propensity score matching, the readmission group still showed a higher P. aeruginosa identification rate (P=0.030), but there was no significant difference in the rate of bacterial identification, with no viral identification (P=0.210). In multivariate analysis, the readmission group showed a higher P. aeruginosa identification rate than the no-readmission group (odds ratio, 4.749; 95% confidence interval, 1.296–17.041; P=0.019). CONCLUSION: P. aeruginosa identification is associated with a higher readmission rate in AECOPD patients.
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spelling pubmed-61746842018-10-15 Pseudomonas aeruginosa infection increases the readmission rate of COPD patients Choi, Juwhan Oh, Jee Youn Lee, Young Seok Hur, Gyu Young Lee, Sung Yong Shim, Jae Jeong Kang, Kyung Ho Min, Kyung Hoon Int J Chron Obstruct Pulmon Dis Original Research INTRODUCTION: Acute exacerbation of COPD (AECOPD) leads to rapid deterioration of pulmonary function and quality of life. It is unclear whether the prognosis for AECOPD differs depending on the bacterium or virus identified. The purpose of this study is to determine whether readmission of patients with severe AECOPD varies according to the bacterium or virus identified. METHODS: We performed a retrospective review of medical records of 704 severe AECOPD events at Korea University Guro Hospital from January 2011 to May 2017. We divided events into two groups, one in which patients were readmitted within 30 days after discharge and the other in which there was no readmission. RESULTS: Of the 704 events, 65 were followed by readmission within 30 days. Before propensity score matching, the readmission group showed a higher rate of bacterial identification with no viral identification and a higher rate of identification with the Pseudomonas aeruginosa (P=0.003 and P=0.007, respectively). Using propensity score matching, the readmission group still showed a higher P. aeruginosa identification rate (P=0.030), but there was no significant difference in the rate of bacterial identification, with no viral identification (P=0.210). In multivariate analysis, the readmission group showed a higher P. aeruginosa identification rate than the no-readmission group (odds ratio, 4.749; 95% confidence interval, 1.296–17.041; P=0.019). CONCLUSION: P. aeruginosa identification is associated with a higher readmission rate in AECOPD patients. Dove Medical Press 2018-10-02 /pmc/articles/PMC6174684/ /pubmed/30323578 http://dx.doi.org/10.2147/COPD.S173759 Text en © 2018 Choi et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Original Research
Choi, Juwhan
Oh, Jee Youn
Lee, Young Seok
Hur, Gyu Young
Lee, Sung Yong
Shim, Jae Jeong
Kang, Kyung Ho
Min, Kyung Hoon
Pseudomonas aeruginosa infection increases the readmission rate of COPD patients
title Pseudomonas aeruginosa infection increases the readmission rate of COPD patients
title_full Pseudomonas aeruginosa infection increases the readmission rate of COPD patients
title_fullStr Pseudomonas aeruginosa infection increases the readmission rate of COPD patients
title_full_unstemmed Pseudomonas aeruginosa infection increases the readmission rate of COPD patients
title_short Pseudomonas aeruginosa infection increases the readmission rate of COPD patients
title_sort pseudomonas aeruginosa infection increases the readmission rate of copd patients
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174684/
https://www.ncbi.nlm.nih.gov/pubmed/30323578
http://dx.doi.org/10.2147/COPD.S173759
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