Cargando…
Pseudomonas aeruginosa infection increases the readmission rate of COPD patients
INTRODUCTION: Acute exacerbation of COPD (AECOPD) leads to rapid deterioration of pulmonary function and quality of life. It is unclear whether the prognosis for AECOPD differs depending on the bacterium or virus identified. The purpose of this study is to determine whether readmission of patients w...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174684/ https://www.ncbi.nlm.nih.gov/pubmed/30323578 http://dx.doi.org/10.2147/COPD.S173759 |
_version_ | 1783361321087008768 |
---|---|
author | Choi, Juwhan Oh, Jee Youn Lee, Young Seok Hur, Gyu Young Lee, Sung Yong Shim, Jae Jeong Kang, Kyung Ho Min, Kyung Hoon |
author_facet | Choi, Juwhan Oh, Jee Youn Lee, Young Seok Hur, Gyu Young Lee, Sung Yong Shim, Jae Jeong Kang, Kyung Ho Min, Kyung Hoon |
author_sort | Choi, Juwhan |
collection | PubMed |
description | INTRODUCTION: Acute exacerbation of COPD (AECOPD) leads to rapid deterioration of pulmonary function and quality of life. It is unclear whether the prognosis for AECOPD differs depending on the bacterium or virus identified. The purpose of this study is to determine whether readmission of patients with severe AECOPD varies according to the bacterium or virus identified. METHODS: We performed a retrospective review of medical records of 704 severe AECOPD events at Korea University Guro Hospital from January 2011 to May 2017. We divided events into two groups, one in which patients were readmitted within 30 days after discharge and the other in which there was no readmission. RESULTS: Of the 704 events, 65 were followed by readmission within 30 days. Before propensity score matching, the readmission group showed a higher rate of bacterial identification with no viral identification and a higher rate of identification with the Pseudomonas aeruginosa (P=0.003 and P=0.007, respectively). Using propensity score matching, the readmission group still showed a higher P. aeruginosa identification rate (P=0.030), but there was no significant difference in the rate of bacterial identification, with no viral identification (P=0.210). In multivariate analysis, the readmission group showed a higher P. aeruginosa identification rate than the no-readmission group (odds ratio, 4.749; 95% confidence interval, 1.296–17.041; P=0.019). CONCLUSION: P. aeruginosa identification is associated with a higher readmission rate in AECOPD patients. |
format | Online Article Text |
id | pubmed-6174684 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-61746842018-10-15 Pseudomonas aeruginosa infection increases the readmission rate of COPD patients Choi, Juwhan Oh, Jee Youn Lee, Young Seok Hur, Gyu Young Lee, Sung Yong Shim, Jae Jeong Kang, Kyung Ho Min, Kyung Hoon Int J Chron Obstruct Pulmon Dis Original Research INTRODUCTION: Acute exacerbation of COPD (AECOPD) leads to rapid deterioration of pulmonary function and quality of life. It is unclear whether the prognosis for AECOPD differs depending on the bacterium or virus identified. The purpose of this study is to determine whether readmission of patients with severe AECOPD varies according to the bacterium or virus identified. METHODS: We performed a retrospective review of medical records of 704 severe AECOPD events at Korea University Guro Hospital from January 2011 to May 2017. We divided events into two groups, one in which patients were readmitted within 30 days after discharge and the other in which there was no readmission. RESULTS: Of the 704 events, 65 were followed by readmission within 30 days. Before propensity score matching, the readmission group showed a higher rate of bacterial identification with no viral identification and a higher rate of identification with the Pseudomonas aeruginosa (P=0.003 and P=0.007, respectively). Using propensity score matching, the readmission group still showed a higher P. aeruginosa identification rate (P=0.030), but there was no significant difference in the rate of bacterial identification, with no viral identification (P=0.210). In multivariate analysis, the readmission group showed a higher P. aeruginosa identification rate than the no-readmission group (odds ratio, 4.749; 95% confidence interval, 1.296–17.041; P=0.019). CONCLUSION: P. aeruginosa identification is associated with a higher readmission rate in AECOPD patients. Dove Medical Press 2018-10-02 /pmc/articles/PMC6174684/ /pubmed/30323578 http://dx.doi.org/10.2147/COPD.S173759 Text en © 2018 Choi et al. This work is published and licensed by Dove Medical Press Limited The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. |
spellingShingle | Original Research Choi, Juwhan Oh, Jee Youn Lee, Young Seok Hur, Gyu Young Lee, Sung Yong Shim, Jae Jeong Kang, Kyung Ho Min, Kyung Hoon Pseudomonas aeruginosa infection increases the readmission rate of COPD patients |
title | Pseudomonas aeruginosa infection increases the readmission rate of COPD patients |
title_full | Pseudomonas aeruginosa infection increases the readmission rate of COPD patients |
title_fullStr | Pseudomonas aeruginosa infection increases the readmission rate of COPD patients |
title_full_unstemmed | Pseudomonas aeruginosa infection increases the readmission rate of COPD patients |
title_short | Pseudomonas aeruginosa infection increases the readmission rate of COPD patients |
title_sort | pseudomonas aeruginosa infection increases the readmission rate of copd patients |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174684/ https://www.ncbi.nlm.nih.gov/pubmed/30323578 http://dx.doi.org/10.2147/COPD.S173759 |
work_keys_str_mv | AT choijuwhan pseudomonasaeruginosainfectionincreasesthereadmissionrateofcopdpatients AT ohjeeyoun pseudomonasaeruginosainfectionincreasesthereadmissionrateofcopdpatients AT leeyoungseok pseudomonasaeruginosainfectionincreasesthereadmissionrateofcopdpatients AT hurgyuyoung pseudomonasaeruginosainfectionincreasesthereadmissionrateofcopdpatients AT leesungyong pseudomonasaeruginosainfectionincreasesthereadmissionrateofcopdpatients AT shimjaejeong pseudomonasaeruginosainfectionincreasesthereadmissionrateofcopdpatients AT kangkyungho pseudomonasaeruginosainfectionincreasesthereadmissionrateofcopdpatients AT minkyunghoon pseudomonasaeruginosainfectionincreasesthereadmissionrateofcopdpatients |