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Origin of the Autophagosome Membrane in Mammals

Autophagy begins with the nucleation of phagophores, which then expand to give rise to the double-membrane autophagosomes. Autophagosomes ultimately fuse with lysosomes, where the cytosolic cargoes are degraded. Accumulation of autophagosomes is a hallmark of autophagy and neurodegenerative disorder...

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Detalles Bibliográficos
Autores principales: Wei, Yun, Liu, Meixia, Li, Xianxiao, Liu, Jiangang, Li, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174804/
https://www.ncbi.nlm.nih.gov/pubmed/30345294
http://dx.doi.org/10.1155/2018/1012789