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Stability, reliability, and validity of the THINC‐it screening tool for cognitive impairment in depression: A psychometric exploration in healthy volunteers

OBJECTIVES: There is a need for a brief, reliable, valid, and sensitive assessment tool for screening cognitive deficits in patients with Major Depressive Disorders. This paper examines the psychometric characteristics of THINC‐it, a cognitive assessment tool composed of four objective measures of c...

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Autores principales: Harrison, John E., Barry, Harry, Baune, Bernhard T., Best, Michael W., Bowie, Christopher R., Cha, Danielle S., Culpepper, Larry, Fossati, Philippe, Greer, Tracy L., Harmer, Catherine, Klag, Esther, Lam, Raymond W., Lee, Yena, Mansur, Rodrigo B., Wittchen, Hans‐Ulrich, McIntyre, Roger S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174931/
https://www.ncbi.nlm.nih.gov/pubmed/30088298
http://dx.doi.org/10.1002/mpr.1736
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author Harrison, John E.
Barry, Harry
Baune, Bernhard T.
Best, Michael W.
Bowie, Christopher R.
Cha, Danielle S.
Culpepper, Larry
Fossati, Philippe
Greer, Tracy L.
Harmer, Catherine
Klag, Esther
Lam, Raymond W.
Lee, Yena
Mansur, Rodrigo B.
Wittchen, Hans‐Ulrich
McIntyre, Roger S.
author_facet Harrison, John E.
Barry, Harry
Baune, Bernhard T.
Best, Michael W.
Bowie, Christopher R.
Cha, Danielle S.
Culpepper, Larry
Fossati, Philippe
Greer, Tracy L.
Harmer, Catherine
Klag, Esther
Lam, Raymond W.
Lee, Yena
Mansur, Rodrigo B.
Wittchen, Hans‐Ulrich
McIntyre, Roger S.
author_sort Harrison, John E.
collection PubMed
description OBJECTIVES: There is a need for a brief, reliable, valid, and sensitive assessment tool for screening cognitive deficits in patients with Major Depressive Disorders. This paper examines the psychometric characteristics of THINC‐it, a cognitive assessment tool composed of four objective measures of cognition and a self‐rated assessment, in subjects without mental disorders. METHODS: N = 100 healthy controls with no current or past history of depression were tested on four sequential assessments to examine temporal stability, reliability, and convergent validity of the THINC‐it tests. We examined temporal reliability across 1 week and stability via three consecutive assessments. Consistency of assessment by the study rater (intrarater reliability) was calculated using the data from the second and third of these consecutive assessments. RESULTS: Test–retest reliability correlations varied between Pearson's r = 0.75 and 0.8. Intrarater reliability between 0.7 and 0.93. Stability for the primary measure for each test yielded within‐subject standard deviation values between 5.9 and 11.23 for accuracy measures and 0.735 and 17.3 seconds for latency measures. Convergent validity for three tasks was in the acceptable range, but low for the Symbol Check task. CONCLUSIONS: Analysis shows high levels of reliability and stability. Levels of convergent validity were modest but acceptable in the case of all but one test.
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spelling pubmed-61749312018-10-15 Stability, reliability, and validity of the THINC‐it screening tool for cognitive impairment in depression: A psychometric exploration in healthy volunteers Harrison, John E. Barry, Harry Baune, Bernhard T. Best, Michael W. Bowie, Christopher R. Cha, Danielle S. Culpepper, Larry Fossati, Philippe Greer, Tracy L. Harmer, Catherine Klag, Esther Lam, Raymond W. Lee, Yena Mansur, Rodrigo B. Wittchen, Hans‐Ulrich McIntyre, Roger S. Int J Methods Psychiatr Res Original Articles OBJECTIVES: There is a need for a brief, reliable, valid, and sensitive assessment tool for screening cognitive deficits in patients with Major Depressive Disorders. This paper examines the psychometric characteristics of THINC‐it, a cognitive assessment tool composed of four objective measures of cognition and a self‐rated assessment, in subjects without mental disorders. METHODS: N = 100 healthy controls with no current or past history of depression were tested on four sequential assessments to examine temporal stability, reliability, and convergent validity of the THINC‐it tests. We examined temporal reliability across 1 week and stability via three consecutive assessments. Consistency of assessment by the study rater (intrarater reliability) was calculated using the data from the second and third of these consecutive assessments. RESULTS: Test–retest reliability correlations varied between Pearson's r = 0.75 and 0.8. Intrarater reliability between 0.7 and 0.93. Stability for the primary measure for each test yielded within‐subject standard deviation values between 5.9 and 11.23 for accuracy measures and 0.735 and 17.3 seconds for latency measures. Convergent validity for three tasks was in the acceptable range, but low for the Symbol Check task. CONCLUSIONS: Analysis shows high levels of reliability and stability. Levels of convergent validity were modest but acceptable in the case of all but one test. John Wiley and Sons Inc. 2018-08-07 /pmc/articles/PMC6174931/ /pubmed/30088298 http://dx.doi.org/10.1002/mpr.1736 Text en © 2018 The Authors International Journal of Methods in Psychiatric Research Published by John Wiley & Sons, Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Articles
Harrison, John E.
Barry, Harry
Baune, Bernhard T.
Best, Michael W.
Bowie, Christopher R.
Cha, Danielle S.
Culpepper, Larry
Fossati, Philippe
Greer, Tracy L.
Harmer, Catherine
Klag, Esther
Lam, Raymond W.
Lee, Yena
Mansur, Rodrigo B.
Wittchen, Hans‐Ulrich
McIntyre, Roger S.
Stability, reliability, and validity of the THINC‐it screening tool for cognitive impairment in depression: A psychometric exploration in healthy volunteers
title Stability, reliability, and validity of the THINC‐it screening tool for cognitive impairment in depression: A psychometric exploration in healthy volunteers
title_full Stability, reliability, and validity of the THINC‐it screening tool for cognitive impairment in depression: A psychometric exploration in healthy volunteers
title_fullStr Stability, reliability, and validity of the THINC‐it screening tool for cognitive impairment in depression: A psychometric exploration in healthy volunteers
title_full_unstemmed Stability, reliability, and validity of the THINC‐it screening tool for cognitive impairment in depression: A psychometric exploration in healthy volunteers
title_short Stability, reliability, and validity of the THINC‐it screening tool for cognitive impairment in depression: A psychometric exploration in healthy volunteers
title_sort stability, reliability, and validity of the thinc‐it screening tool for cognitive impairment in depression: a psychometric exploration in healthy volunteers
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174931/
https://www.ncbi.nlm.nih.gov/pubmed/30088298
http://dx.doi.org/10.1002/mpr.1736
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