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Noncoding RNAs in disease

Noncoding RNAs are emerging as potent and multifunctional regulators in all biological processes. In parallel, a rapidly growing number of studies has unravelled associations between aberrant noncoding RNA expression and human diseases. These associations have been extensively reviewed, often with t...

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Detalles Bibliográficos
Autores principales: Lekka, Evangelia, Hall, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174949/
https://www.ncbi.nlm.nih.gov/pubmed/29972883
http://dx.doi.org/10.1002/1873-3468.13182
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author Lekka, Evangelia
Hall, Jonathan
author_facet Lekka, Evangelia
Hall, Jonathan
author_sort Lekka, Evangelia
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description Noncoding RNAs are emerging as potent and multifunctional regulators in all biological processes. In parallel, a rapidly growing number of studies has unravelled associations between aberrant noncoding RNA expression and human diseases. These associations have been extensively reviewed, often with the focus on a particular microRNA (miRNA) (family) or a selected disease/pathology. In this Mini‐Review, we highlight a selection of studies in order to demonstrate the wide‐scale involvement of miRNAs and long noncoding RNAs in the pathophysiology of three types of diseases: cancer, cardiovascular and neurological disorders. This research is opening new avenues to novel therapeutic approaches.
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spelling pubmed-61749492018-10-15 Noncoding RNAs in disease Lekka, Evangelia Hall, Jonathan FEBS Lett Review Articles Noncoding RNAs are emerging as potent and multifunctional regulators in all biological processes. In parallel, a rapidly growing number of studies has unravelled associations between aberrant noncoding RNA expression and human diseases. These associations have been extensively reviewed, often with the focus on a particular microRNA (miRNA) (family) or a selected disease/pathology. In this Mini‐Review, we highlight a selection of studies in order to demonstrate the wide‐scale involvement of miRNAs and long noncoding RNAs in the pathophysiology of three types of diseases: cancer, cardiovascular and neurological disorders. This research is opening new avenues to novel therapeutic approaches. John Wiley and Sons Inc. 2018-07-20 2018-09 /pmc/articles/PMC6174949/ /pubmed/29972883 http://dx.doi.org/10.1002/1873-3468.13182 Text en © The Authors. FEBS Letters published by John Wiley & Sons Ltd on behalf of Federation of European Biochemical Societies This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Articles
Lekka, Evangelia
Hall, Jonathan
Noncoding RNAs in disease
title Noncoding RNAs in disease
title_full Noncoding RNAs in disease
title_fullStr Noncoding RNAs in disease
title_full_unstemmed Noncoding RNAs in disease
title_short Noncoding RNAs in disease
title_sort noncoding rnas in disease
topic Review Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174949/
https://www.ncbi.nlm.nih.gov/pubmed/29972883
http://dx.doi.org/10.1002/1873-3468.13182
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