Chromosomal rearrangements in uveal melanoma: Chromothripsis

Uveal melanoma (UM) is the most common primary intraocular malignancy in the Western world. Recurrent mutations in GNAQ, GNA11, CYSLTR2, PLCB4, BAP1, EIF1AX, and SF3B1 are described as well as non‐random chromosomal aberrations. Chromothripsis is a rare event in which chromosomes are shattered and r...

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Detalles Bibliográficos
Autores principales: van Poppelen, Natasha M., Yavuzyigitoglu, Serdar, Smit, Kyra N., Vaarwater, Jolanda, Eussen, Bert, Brands, Tom, Paridaens, Dion, Kiliç, Emine, de Klein, Annelies
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons, Inc. 2018
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175119/
https://www.ncbi.nlm.nih.gov/pubmed/29726589
http://dx.doi.org/10.1002/gcc.4

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