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Molecular progression to cervical precancer, epigenetic switch or sequential model?

The evolution of precancerous cervical lesions is poorly understood. A widely held model of cervical intraepithelial neoplasia grade 3 (CIN3) development is sequential progression from normal through CIN1 and CIN2 to CIN3. Another hypothesis, the “molecular switch” model, postulates that CIN3 can ev...

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Detalles Bibliográficos
Autores principales:	Nedjai, Belinda, Reuter, Caroline, Ahmad, Amar, Banwait, Rawinder, Warman, Rhian, Carton, James, Boer, Sabrina, Cuzick, Jack, Lorincz, Attila T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Cancer Genetics and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175180/ https://www.ncbi.nlm.nih.gov/pubmed/29679470 http://dx.doi.org/10.1002/ijc.31549

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