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Biochemical efficacy of tioguanine in autoimmune hepatitis: a retrospective review of practice in the Netherlands

BACKGROUND: Azathioprine (AZA) and mercaptopurine (MP) are the cornerstone of steroid‐sparing strategies in autoimmune hepatitis (AIH). Up to 20% of patients do not tolerate or respond to these regimens. AIM: To evaluate retrospectively the tolerability and efficacy of tioguanine (thioguanine) (TG)...

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Detalles Bibliográficos
Autores principales: van den Brand, Floris F., van Nieuwkerk, Carin M. J., Verwer, Bart J., de Boer, Ynto S., de Boer, Nanne K. H., Mulder, Chris J. J., Bloemena, Elisabeth, Bakker, Christine M., Vrolijk, Jan M., Drenth, Joost P. H., Tan, Adriaan C. I. T. L., ter Borg, Frank, ter Borg, Martijn J., van den Hazel, Sven J., Inderson, Akin, Tushuizen, Maarten E., Bouma, Gerd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175236/
https://www.ncbi.nlm.nih.gov/pubmed/30109891
http://dx.doi.org/10.1111/apt.14939