Early‐life regional and temporal variation in filaggrin‐derived natural moisturizing factor, filaggrin‐processing enzyme activity, corneocyte phenotypes and plasmin activity: implications for atopic dermatitis

BACKGROUND: Filaggrin is central to the pathogenesis of atopic dermatitis (AD). The cheeks are a common initiation site of infantile AD. Regional and temporal expression of levels of filaggrin degradation products [natural moisturizing factors (NMFs)], activities of filaggrin‐processing enzymes [ble...

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Detalles Bibliográficos
Autores principales: McAleer, M.A., Jakasa, I., Raj, N., O'Donnell, C.P.F., Lane, M.E., Rawlings, A.V., Voegeli, R., McLean, W.H.I., Kezic, S., Irvine, A.D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175251/
https://www.ncbi.nlm.nih.gov/pubmed/29691836
http://dx.doi.org/10.1111/bjd.16691

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