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Impact of bistrand abasic sites and proximate orientation on DNA global structure and duplex energetics

Bistrand lesions embedded within a single helical turn of tridecameric deoxyoligonucleotide duplexes represent a model system for exploring the impact of clustered lesions that occur in vivo and pose a significant challenge to cellular repair machineries. Such investigations are essential for unders...

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Detalles Bibliográficos
Autores principales:	Minetti, Conceição A., Sun, Jeffrey Y., Jacobs, Daniel P., Kang, Inkoo, Remeta, David P., Breslauer, Kenneth J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175389/ https://www.ncbi.nlm.nih.gov/pubmed/29322505 http://dx.doi.org/10.1002/bip.23098

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