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An information theoretic treatment of sequence-to-expression modeling
Studying a gene’s regulatory mechanisms is a tedious process that involves identification of candidate regulators by transcription factor (TF) knockout or over-expression experiments, delineation of enhancers by reporter assays, and demonstration of direct TF influence by site mutagenesis, among oth...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175532/ https://www.ncbi.nlm.nih.gov/pubmed/30256780 http://dx.doi.org/10.1371/journal.pcbi.1006459 |