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Sex-Gender Differences in Irritable Bowel Syndrome
Because of the sex-gender differences that are shown in a diversity of physiological and psychological factors, it can be speculated that the clinical presentation of symptoms as well as treatment strategies in women and men with irritable bowel syndrome (IBS) may differ. Studies have revealed that...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Korean Society of Neurogastroenterology and Motility
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175559/ https://www.ncbi.nlm.nih.gov/pubmed/30347934 http://dx.doi.org/10.5056/jnm18082 |
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author | Kim, Young Sun Kim, Nayoung |
author_facet | Kim, Young Sun Kim, Nayoung |
author_sort | Kim, Young Sun |
collection | PubMed |
description | Because of the sex-gender differences that are shown in a diversity of physiological and psychological factors, it can be speculated that the clinical presentation of symptoms as well as treatment strategies in women and men with irritable bowel syndrome (IBS) may differ. Studies have revealed that IBS is more common in women than men. As for the IBS subtype, IBS with constipation is significantly more prevalent among women than men. Sex hormones and gender differences may play important roles in the pathophysiology of IBS. However, its pathophysiologic mechanisms still remain largely unknown, and therapeutic implications are limited. Moreover, women IBS patients have been reported to feel more fatigue, depression, anxiety, and lower quality of life than men IBS patients. Furthermore, there has been evidence of differences in the appropriate treatment efficacy to IBS in men and women, although relatively few men are enrolled in most relevant clinical trials. A more sex-gender-oriented approach in the medical care setting could improve understanding of heterogeneous patients suffering from IBS. An individualized and multicomponent approach including sex and gender issues might help improve the treatment of IBS. |
format | Online Article Text |
id | pubmed-6175559 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Korean Society of Neurogastroenterology and Motility |
record_format | MEDLINE/PubMed |
spelling | pubmed-61755592018-10-17 Sex-Gender Differences in Irritable Bowel Syndrome Kim, Young Sun Kim, Nayoung J Neurogastroenterol Motil Review Because of the sex-gender differences that are shown in a diversity of physiological and psychological factors, it can be speculated that the clinical presentation of symptoms as well as treatment strategies in women and men with irritable bowel syndrome (IBS) may differ. Studies have revealed that IBS is more common in women than men. As for the IBS subtype, IBS with constipation is significantly more prevalent among women than men. Sex hormones and gender differences may play important roles in the pathophysiology of IBS. However, its pathophysiologic mechanisms still remain largely unknown, and therapeutic implications are limited. Moreover, women IBS patients have been reported to feel more fatigue, depression, anxiety, and lower quality of life than men IBS patients. Furthermore, there has been evidence of differences in the appropriate treatment efficacy to IBS in men and women, although relatively few men are enrolled in most relevant clinical trials. A more sex-gender-oriented approach in the medical care setting could improve understanding of heterogeneous patients suffering from IBS. An individualized and multicomponent approach including sex and gender issues might help improve the treatment of IBS. Korean Society of Neurogastroenterology and Motility 2018-10 2018-10-01 /pmc/articles/PMC6175559/ /pubmed/30347934 http://dx.doi.org/10.5056/jnm18082 Text en © 2018 The Korean Society of Neurogastroenterology and Motility This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Kim, Young Sun Kim, Nayoung Sex-Gender Differences in Irritable Bowel Syndrome |
title | Sex-Gender Differences in Irritable Bowel Syndrome |
title_full | Sex-Gender Differences in Irritable Bowel Syndrome |
title_fullStr | Sex-Gender Differences in Irritable Bowel Syndrome |
title_full_unstemmed | Sex-Gender Differences in Irritable Bowel Syndrome |
title_short | Sex-Gender Differences in Irritable Bowel Syndrome |
title_sort | sex-gender differences in irritable bowel syndrome |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175559/ https://www.ncbi.nlm.nih.gov/pubmed/30347934 http://dx.doi.org/10.5056/jnm18082 |
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