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Screening of medium constituents for clavulanic acid production by Streptomyces clavuligerus
Clavulanic acid is a β-lactam compound with potent inhibitory activity against β-lactamases. Studies have shown that certain amino acids play essential roles in CA biosynthesis. However, quantitative evaluations of the effects of these amino acids are still needed in order to improve CA production....
Autores principales: | Rodrigues, Kaio César da Silva, Souza, Arianne Tairyne de, Badino, Alberto Colli, Pedrolli, Danielle Biscaro, Cerri, Marcel Otavio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175696/ https://www.ncbi.nlm.nih.gov/pubmed/29588197 http://dx.doi.org/10.1016/j.bjm.2018.01.006 |
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