IgG4-related disease presenting with combined pulmonary fibrosis and emphysema (CPFE)

A 64-year-old man was admitted to our hospital with an abnormal chest shadow. The patient was a current-smoker and had a past illness of autoimmune pancreatitis with a high serum level of IgG4, 348 mg/dL. Chest CT showed upper-lobe emphysema, and lower-lobe reticulation with honeycombing, suggestive...

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Autores principales: Kono, Masato, Nakamura, Yutaro, Oyama, Yoshiyuki, Saito, Go, Koyanagi, Yu, Miyashita, Koichi, Tsutsumi, Akari, Enomoto, Yasunori, Kobayashi, Takeshi, Miki, Yoshihiro, Hashimoto, Dai, Enomoto, Noriyuki, Colby, Thomas V., Suda, Takafumi, Nakamura, Hidenori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175766/
https://www.ncbi.nlm.nih.gov/pubmed/30302309
http://dx.doi.org/10.1016/j.rmcr.2018.09.017
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author Kono, Masato
Nakamura, Yutaro
Oyama, Yoshiyuki
Saito, Go
Koyanagi, Yu
Miyashita, Koichi
Tsutsumi, Akari
Enomoto, Yasunori
Kobayashi, Takeshi
Miki, Yoshihiro
Hashimoto, Dai
Enomoto, Noriyuki
Colby, Thomas V.
Suda, Takafumi
Nakamura, Hidenori
author_facet Kono, Masato
Nakamura, Yutaro
Oyama, Yoshiyuki
Saito, Go
Koyanagi, Yu
Miyashita, Koichi
Tsutsumi, Akari
Enomoto, Yasunori
Kobayashi, Takeshi
Miki, Yoshihiro
Hashimoto, Dai
Enomoto, Noriyuki
Colby, Thomas V.
Suda, Takafumi
Nakamura, Hidenori
author_sort Kono, Masato
collection PubMed
description A 64-year-old man was admitted to our hospital with an abnormal chest shadow. The patient was a current-smoker and had a past illness of autoimmune pancreatitis with a high serum level of IgG4, 348 mg/dL. Chest CT showed upper-lobe emphysema, and lower-lobe reticulation with honeycombing, suggestive of combined pulmonary fibrosis with emphysema (CPFE). Surgical lung biopsy was revealed a usual interstitial pneumonia pattern with marked infiltration of IgG4-positive plasma cells. The patient was diagnosed with IgG4 related disease (IgG4-RD) presenting with CPFE. Pulmonary manifestation was improved by corticosteroid therapy. IgG4-RD may be an underlying condition in patient with CPFE.
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spelling pubmed-61757662018-10-09 IgG4-related disease presenting with combined pulmonary fibrosis and emphysema (CPFE) Kono, Masato Nakamura, Yutaro Oyama, Yoshiyuki Saito, Go Koyanagi, Yu Miyashita, Koichi Tsutsumi, Akari Enomoto, Yasunori Kobayashi, Takeshi Miki, Yoshihiro Hashimoto, Dai Enomoto, Noriyuki Colby, Thomas V. Suda, Takafumi Nakamura, Hidenori Respir Med Case Rep Case Report A 64-year-old man was admitted to our hospital with an abnormal chest shadow. The patient was a current-smoker and had a past illness of autoimmune pancreatitis with a high serum level of IgG4, 348 mg/dL. Chest CT showed upper-lobe emphysema, and lower-lobe reticulation with honeycombing, suggestive of combined pulmonary fibrosis with emphysema (CPFE). Surgical lung biopsy was revealed a usual interstitial pneumonia pattern with marked infiltration of IgG4-positive plasma cells. The patient was diagnosed with IgG4 related disease (IgG4-RD) presenting with CPFE. Pulmonary manifestation was improved by corticosteroid therapy. IgG4-RD may be an underlying condition in patient with CPFE. Elsevier 2018-10-03 /pmc/articles/PMC6175766/ /pubmed/30302309 http://dx.doi.org/10.1016/j.rmcr.2018.09.017 Text en © 2018 The Authors. Published by Elsevier Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Kono, Masato
Nakamura, Yutaro
Oyama, Yoshiyuki
Saito, Go
Koyanagi, Yu
Miyashita, Koichi
Tsutsumi, Akari
Enomoto, Yasunori
Kobayashi, Takeshi
Miki, Yoshihiro
Hashimoto, Dai
Enomoto, Noriyuki
Colby, Thomas V.
Suda, Takafumi
Nakamura, Hidenori
IgG4-related disease presenting with combined pulmonary fibrosis and emphysema (CPFE)
title IgG4-related disease presenting with combined pulmonary fibrosis and emphysema (CPFE)
title_full IgG4-related disease presenting with combined pulmonary fibrosis and emphysema (CPFE)
title_fullStr IgG4-related disease presenting with combined pulmonary fibrosis and emphysema (CPFE)
title_full_unstemmed IgG4-related disease presenting with combined pulmonary fibrosis and emphysema (CPFE)
title_short IgG4-related disease presenting with combined pulmonary fibrosis and emphysema (CPFE)
title_sort igg4-related disease presenting with combined pulmonary fibrosis and emphysema (cpfe)
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175766/
https://www.ncbi.nlm.nih.gov/pubmed/30302309
http://dx.doi.org/10.1016/j.rmcr.2018.09.017
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