Cargando…
Haplosaurus computes protein haplotypes for use in precision drug design
Selecting the most appropriate protein sequences is critical for precision drug design. Here we describe Haplosaurus, a bioinformatic tool for computation of protein haplotypes. Haplosaurus computes protein haplotypes from pre-existing chromosomally-phased genomic variation data. Integration into th...
Autores principales: | Spooner, William, McLaren, William, Slidel, Timothy, Finch, Donna K., Butler, Robin, Campbell, Jamie, Eghobamien, Laura, Rider, David, Kiefer, Christine Mione, Robinson, Matthew J., Hardman, Colin, Cunningham, Fiona, Vaughan, Tristan, Flicek, Paul, Huntington, Catherine Chaillan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175845/ https://www.ncbi.nlm.nih.gov/pubmed/30297836 http://dx.doi.org/10.1038/s41467-018-06542-1 |
Ejemplares similares
-
Deriving the consequences of genomic variants with the Ensembl API and SNP Effect Predictor
por: McLaren, William, et al.
Publicado: (2010) -
A database and API for variation, dense genotyping and resequencing data
por: Rios, Daniel, et al.
Publicado: (2010) -
The Ensembl Variant Effect Predictor
por: McLaren, William, et al.
Publicado: (2016) -
Ensembl variation resources
por: Hunt, Sarah E, et al.
Publicado: (2018) -
Locus Reference Genomic sequences: an improved basis for describing human DNA variants
por: Dalgleish, Raymond, et al.
Publicado: (2010)