Epigenomic map of human liver reveals principles of zonated morphogenic and metabolic control

A deeper epigenomic understanding of spatial organization of cells in human tissues is an important challenge. Here we report the first combined positional analysis of transcriptomes and methylomes across three micro-dissected zones (pericentral, intermediate and periportal) of human liver. We ident...

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Detalles Bibliográficos
Autores principales: Brosch, Mario, Kattler, Kathrin, Herrmann, Alexander, von Schönfels, Witigo, Nordström, Karl, Seehofer, Daniel, Damm, Georg, Becker, Thomas, Zeissig, Sebastian, Nehring, Sophie, Reichel, Fabian, Moser, Vincent, Thangapandi, Raghavan Veera, Stickel, Felix, Baretton, Gustavo, Röcken, Christoph, Muders, Michael, Matz-Soja, Madlen, Krawczak, Michael, Gasparoni, Gilles, Hartmann, Hella, Dahl, Andreas, Schafmayer, Clemens, Walter, Jörn, Hampe, Jochen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175862/
https://www.ncbi.nlm.nih.gov/pubmed/30297808
http://dx.doi.org/10.1038/s41467-018-06611-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175862/
https://www.ncbi.nlm.nih.gov/pubmed/30297808
http://dx.doi.org/10.1038/s41467-018-06611-5

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