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LINCS L1000 dataset-based repositioning of CGP-60474 as a highly potent anti-endotoxemic agent
Sepsis is one of the most common clinical syndromes that causes death and disability. Although many studies have developed drugs for sepsis treatment, none have decreased the mortality rate. The aim of this study was to identify a novel treatment option for sepsis using the library of integrated net...
Autores principales: | Han, Hyun-Wook, Hahn, Soojung, Jeong, Hye Yun, Jee, Joo-Hyun, Nam, Myoung-Ok, Kim, Han Kyung, Lee, Dong Hyeon, Lee, So-Young, Choi, Dong Kyu, Yu, Ji Hoon, Min, Sang-Hyun, Yoo, Jongman |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175892/ https://www.ncbi.nlm.nih.gov/pubmed/30297806 http://dx.doi.org/10.1038/s41598-018-33039-0 |
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