Elevated expression of a minor isoform of ANK3 is a risk factor for bipolar disorder

Ankyrin-3 (ANK3) is one of the few genes that have been consistently identified as associated with bipolar disorder by multiple genome-wide association studies. However, the exact molecular basis of the association remains unknown. A rare loss-of-function splice-site SNP (rs41283526*G) in a minor is...

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Detalles Bibliográficos
Autores principales: Hughes, Timothy, Sønderby, Ida E., Polushina, Tatiana, Hansson, Lars, Holmgren, Asbjørn, Athanasiu, Lavinia, Melbø-Jørgensen, Christian, Hassani, Sahar, Hoeffding, Louise K., Herms, Stefan, Bergen, Sarah E., Karlsson, Robert, Song, Jie, Rietschel, Marcella, Nöthen, Markus M., Forstner, Andreas J., Hoffmann, Per, Hultman, Christina M., Landén, Mikael, Cichon, Sven, Werge, Thomas, Andreassen, Ole A., Le Hellard, Stephanie, Djurovic, Srdjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175894/
https://www.ncbi.nlm.nih.gov/pubmed/30297702
http://dx.doi.org/10.1038/s41398-018-0175-x

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