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The mycoparasitic yeast Saccharomycopsis schoenii predates and kills multi-drug resistant Candida auris

Candida auris has recently emerged as a multi-drug resistant fungal pathogen that poses a serious global health threat, especially for patients in hospital intensive care units (ICUs). C. auris can colonize human skin and can spread by physical contact or contaminated surfaces and equipment. Here, w...

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Detalles Bibliográficos
Autores principales: Junker, Klara, Bravo Ruiz, Gustavo, Lorenz, Alexander, Walker, Louise, Gow, Neil A. R., Wendland, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175896/
https://www.ncbi.nlm.nih.gov/pubmed/30297756
http://dx.doi.org/10.1038/s41598-018-33199-z
Descripción
Sumario:Candida auris has recently emerged as a multi-drug resistant fungal pathogen that poses a serious global health threat, especially for patients in hospital intensive care units (ICUs). C. auris can colonize human skin and can spread by physical contact or contaminated surfaces and equipment. Here, we show that the mycoparasitic yeast Saccharomycopsis schoenii efficiently kills both sensitive and multi-drug resistant isolates of C. auris belonging to the same clade, as well as clinical isolates of other pathogenic species of the Candida genus suggesting novel approaches for biocontrol.