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The mycoparasitic yeast Saccharomycopsis schoenii predates and kills multi-drug resistant Candida auris
Candida auris has recently emerged as a multi-drug resistant fungal pathogen that poses a serious global health threat, especially for patients in hospital intensive care units (ICUs). C. auris can colonize human skin and can spread by physical contact or contaminated surfaces and equipment. Here, w...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175896/ https://www.ncbi.nlm.nih.gov/pubmed/30297756 http://dx.doi.org/10.1038/s41598-018-33199-z |
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author | Junker, Klara Bravo Ruiz, Gustavo Lorenz, Alexander Walker, Louise Gow, Neil A. R. Wendland, Jürgen |
author_facet | Junker, Klara Bravo Ruiz, Gustavo Lorenz, Alexander Walker, Louise Gow, Neil A. R. Wendland, Jürgen |
author_sort | Junker, Klara |
collection | PubMed |
description | Candida auris has recently emerged as a multi-drug resistant fungal pathogen that poses a serious global health threat, especially for patients in hospital intensive care units (ICUs). C. auris can colonize human skin and can spread by physical contact or contaminated surfaces and equipment. Here, we show that the mycoparasitic yeast Saccharomycopsis schoenii efficiently kills both sensitive and multi-drug resistant isolates of C. auris belonging to the same clade, as well as clinical isolates of other pathogenic species of the Candida genus suggesting novel approaches for biocontrol. |
format | Online Article Text |
id | pubmed-6175896 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-61758962018-10-12 The mycoparasitic yeast Saccharomycopsis schoenii predates and kills multi-drug resistant Candida auris Junker, Klara Bravo Ruiz, Gustavo Lorenz, Alexander Walker, Louise Gow, Neil A. R. Wendland, Jürgen Sci Rep Article Candida auris has recently emerged as a multi-drug resistant fungal pathogen that poses a serious global health threat, especially for patients in hospital intensive care units (ICUs). C. auris can colonize human skin and can spread by physical contact or contaminated surfaces and equipment. Here, we show that the mycoparasitic yeast Saccharomycopsis schoenii efficiently kills both sensitive and multi-drug resistant isolates of C. auris belonging to the same clade, as well as clinical isolates of other pathogenic species of the Candida genus suggesting novel approaches for biocontrol. Nature Publishing Group UK 2018-10-08 /pmc/articles/PMC6175896/ /pubmed/30297756 http://dx.doi.org/10.1038/s41598-018-33199-z Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Junker, Klara Bravo Ruiz, Gustavo Lorenz, Alexander Walker, Louise Gow, Neil A. R. Wendland, Jürgen The mycoparasitic yeast Saccharomycopsis schoenii predates and kills multi-drug resistant Candida auris |
title | The mycoparasitic yeast Saccharomycopsis schoenii predates and kills multi-drug resistant Candida auris |
title_full | The mycoparasitic yeast Saccharomycopsis schoenii predates and kills multi-drug resistant Candida auris |
title_fullStr | The mycoparasitic yeast Saccharomycopsis schoenii predates and kills multi-drug resistant Candida auris |
title_full_unstemmed | The mycoparasitic yeast Saccharomycopsis schoenii predates and kills multi-drug resistant Candida auris |
title_short | The mycoparasitic yeast Saccharomycopsis schoenii predates and kills multi-drug resistant Candida auris |
title_sort | mycoparasitic yeast saccharomycopsis schoenii predates and kills multi-drug resistant candida auris |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175896/ https://www.ncbi.nlm.nih.gov/pubmed/30297756 http://dx.doi.org/10.1038/s41598-018-33199-z |
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