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Synergy between intrinsically disordered domains and structured proteins amplifies membrane curvature sensing

The ability of proteins to sense membrane curvature is essential to cellular function. All known sensing mechanisms rely on protein domains with specific structural features such as wedge-like amphipathic helices and crescent-shaped BAR domains. Yet many proteins that contain these domains also cont...

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Detalles Bibliográficos
Autores principales: Zeno, Wade F., Baul, Upayan, Snead, Wilton T., DeGroot, Andre C. M., Wang, Liping, Lafer, Eileen M., Thirumalai, D., Stachowiak, Jeanne C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175956/
https://www.ncbi.nlm.nih.gov/pubmed/30297718
http://dx.doi.org/10.1038/s41467-018-06532-3

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