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Both Monoclonal and Polyclonal Immunoglobulin Contingents Mediate Complement Activation in Monoclonal Gammopathy Associated-C3 Glomerulopathy

C3 glomerulopathy (C3G) results from acquired or genetic abnormalities in the complement alternative pathway (AP). C3G with monoclonal immunoglobulin (MIg-C3G) was recently included in the spectrum of “monoclonal gammopathy of renal significance.” However, mechanisms of complement dysregulation in M...

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Detalles Bibliográficos
Autores principales:	Chauvet, Sophie, Roumenina, Lubka T., Aucouturier, Pierre, Marinozzi, Maria-Chiara, Dragon-Durey, Marie-Agnès, Karras, Alexandre, Delmas, Yahsou, Le Quintrec, Moglie, Guerrot, Dominique, Jourde-Chiche, Noémie, Ribes, David, Ronco, Pierre, Bridoux, Frank, Fremeaux-Bacchi, Véronique
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175995/ https://www.ncbi.nlm.nih.gov/pubmed/30333829 http://dx.doi.org/10.3389/fimmu.2018.02260

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