iNKT Cells Suppress Pathogenic NK1.1(+)CD8(+) T Cells in DSS-Induced Colitis

T cells producing IFNγ play a pathogenic role in the development of inflammatory bowel disease (IBD). To investigate the functions of CD1d-dependent invariant natural killer T (iNKT) cells in experimental colitis induced in Yeti mice with dysregulated expression of IFNγ, we generated iNKT cell-defic...

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Detalles Bibliográficos
Autores principales: Lee, Sung Won, Park, Hyun Jung, Cheon, Jae Hee, Wu, Lan, Van Kaer, Luc, Hong, Seokmann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176072/
https://www.ncbi.nlm.nih.gov/pubmed/30333822
http://dx.doi.org/10.3389/fimmu.2018.02168

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176072/
https://www.ncbi.nlm.nih.gov/pubmed/30333822
http://dx.doi.org/10.3389/fimmu.2018.02168

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