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iNKT Cells Suppress Pathogenic NK1.1(+)CD8(+) T Cells in DSS-Induced Colitis
T cells producing IFNγ play a pathogenic role in the development of inflammatory bowel disease (IBD). To investigate the functions of CD1d-dependent invariant natural killer T (iNKT) cells in experimental colitis induced in Yeti mice with dysregulated expression of IFNγ, we generated iNKT cell-defic...
Autores principales: | Lee, Sung Won, Park, Hyun Jung, Cheon, Jae Hee, Wu, Lan, Van Kaer, Luc, Hong, Seokmann |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176072/ https://www.ncbi.nlm.nih.gov/pubmed/30333822 http://dx.doi.org/10.3389/fimmu.2018.02168 |
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