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Conventional Anti-glioblastoma Chemotherapy Affects Proteoglycan Composition of Brain Extracellular Matrix in Rat Experimental Model in vivo
Temozolomide (TMZ) is a conventional chemotherapy drug for adjuvant treatment of glioblastoma multiforme (GBM), often accompanied by dexamethasone (DXM) to prevent brain oedema and alleviate clinical side effects. Here, we aimed to investigate an ability of the drugs to affect normal brain tissue in...
Autores principales: | Tsidulko, Alexandra Y., Bezier, Cynthia, de La Bourdonnaye, Gabin, Suhovskih, Anastasia V., Pankova, Tatiana M., Kazanskaya, Galina M., Aidagulova, Svetlana V., Grigorieva, Elvira V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176078/ https://www.ncbi.nlm.nih.gov/pubmed/30333749 http://dx.doi.org/10.3389/fphar.2018.01104 |
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