Growth Hormone (GH) Deficient Mice With GHRH Gene Ablation Are Severely Deficient in Vaccine and Immune Responses Against Streptococcus pneumoniae

The precise impact of the somatotrope axis upon the immune system is still highly debated. We have previously shown that mice with generalized ablation of growth hormone (GH) releasing hormone (GHRH) gene (Ghrh(−/−)) have normal thymus and T-cell development, but present a marked spleen atrophy and...

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Detalles Bibliográficos
Autores principales: Farhat, Khalil, Bodart, Gwennaëlle, Charlet-Renard, Chantal, Desmet, Christophe J., Moutschen, Michel, Beguin, Yves, Baron, Frédéric, Melin, Pierrette, Quatresooz, Pascale, Parent, Anne-Simone, Desmecht, Daniel, Sirard, Jean-Claude, Salvatori, Roberto, Martens, Henri, Geenen, Vincent G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176084/
https://www.ncbi.nlm.nih.gov/pubmed/30333823
http://dx.doi.org/10.3389/fimmu.2018.02175

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176084/
https://www.ncbi.nlm.nih.gov/pubmed/30333823
http://dx.doi.org/10.3389/fimmu.2018.02175

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