Cargando…
Retrospective Evaluation of Bayesian Risk Models of LVAD Mortality at a Single Implant Center
Use of a left ventricular assist device (LVAD) can benefit patients with end stage heart failure, but only with careful patient selection. In this study, previously derived Bayesian network models for predicting LVAD patient mortality at 1, 3, and 12 months post-implant were evaluated on retrospecti...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176112/ https://www.ncbi.nlm.nih.gov/pubmed/30333978 http://dx.doi.org/10.3389/fmed.2018.00277 |
_version_ | 1783361642751328256 |
---|---|
author | Lohmueller, Lisa C. Kanwar, Manreet K. Bailey, Stephen Murali, Srinivas Antaki, James F. |
author_facet | Lohmueller, Lisa C. Kanwar, Manreet K. Bailey, Stephen Murali, Srinivas Antaki, James F. |
author_sort | Lohmueller, Lisa C. |
collection | PubMed |
description | Use of a left ventricular assist device (LVAD) can benefit patients with end stage heart failure, but only with careful patient selection. In this study, previously derived Bayesian network models for predicting LVAD patient mortality at 1, 3, and 12 months post-implant were evaluated on retrospective data from a single implant center. The models performed well at all three time points, with a receiver operating characteristic area under the curve (ROC AUC) of 78, 76, and 75%, respectively. This evaluation of model performance verifies the utility of these models in “real life” scenarios at an individual institution. |
format | Online Article Text |
id | pubmed-6176112 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-61761122018-10-17 Retrospective Evaluation of Bayesian Risk Models of LVAD Mortality at a Single Implant Center Lohmueller, Lisa C. Kanwar, Manreet K. Bailey, Stephen Murali, Srinivas Antaki, James F. Front Med (Lausanne) Medicine Use of a left ventricular assist device (LVAD) can benefit patients with end stage heart failure, but only with careful patient selection. In this study, previously derived Bayesian network models for predicting LVAD patient mortality at 1, 3, and 12 months post-implant were evaluated on retrospective data from a single implant center. The models performed well at all three time points, with a receiver operating characteristic area under the curve (ROC AUC) of 78, 76, and 75%, respectively. This evaluation of model performance verifies the utility of these models in “real life” scenarios at an individual institution. Frontiers Media S.A. 2018-10-02 /pmc/articles/PMC6176112/ /pubmed/30333978 http://dx.doi.org/10.3389/fmed.2018.00277 Text en Copyright © 2018 Lohmueller, Kanwar, Bailey, Murali and Antaki. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Medicine Lohmueller, Lisa C. Kanwar, Manreet K. Bailey, Stephen Murali, Srinivas Antaki, James F. Retrospective Evaluation of Bayesian Risk Models of LVAD Mortality at a Single Implant Center |
title | Retrospective Evaluation of Bayesian Risk Models of LVAD Mortality at a Single Implant Center |
title_full | Retrospective Evaluation of Bayesian Risk Models of LVAD Mortality at a Single Implant Center |
title_fullStr | Retrospective Evaluation of Bayesian Risk Models of LVAD Mortality at a Single Implant Center |
title_full_unstemmed | Retrospective Evaluation of Bayesian Risk Models of LVAD Mortality at a Single Implant Center |
title_short | Retrospective Evaluation of Bayesian Risk Models of LVAD Mortality at a Single Implant Center |
title_sort | retrospective evaluation of bayesian risk models of lvad mortality at a single implant center |
topic | Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176112/ https://www.ncbi.nlm.nih.gov/pubmed/30333978 http://dx.doi.org/10.3389/fmed.2018.00277 |
work_keys_str_mv | AT lohmuellerlisac retrospectiveevaluationofbayesianriskmodelsoflvadmortalityatasingleimplantcenter AT kanwarmanreetk retrospectiveevaluationofbayesianriskmodelsoflvadmortalityatasingleimplantcenter AT baileystephen retrospectiveevaluationofbayesianriskmodelsoflvadmortalityatasingleimplantcenter AT muralisrinivas retrospectiveevaluationofbayesianriskmodelsoflvadmortalityatasingleimplantcenter AT antakijamesf retrospectiveevaluationofbayesianriskmodelsoflvadmortalityatasingleimplantcenter |