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Characterization of Inducible Transcription and Translation-Competent HIV-1 Using the RNAscope ISH Technology at a Single-Cell Resolution

Identifying the source and dynamics of persistent HIV-1 at single-cell resolution during cART is crucial for the design of strategies to eliminate the latent HIV-1 reservoir. An assay to measure latent HIV-1 that can distinguish inducible from defective proviruses with high precision is essential to...

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Detalles Bibliográficos
Autores principales:	Zhang, Wang, Svensson Akusjärvi, Sara, Sönnerborg, Anders, Neogi, Ujjwal
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176121/ https://www.ncbi.nlm.nih.gov/pubmed/30333813 http://dx.doi.org/10.3389/fmicb.2018.02358

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