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Highly selective peripheral nerve radio frequency ablation for the treatment of severe knee osteoarthritis
The objective of the present study was to investigate the effect of highly selective peripheral nerve radiofrequency (RF) ablation for the pain caused by severe knee osteoarthritis (OA). A total of 96 patients with knee OA were randomly divided into two groups. The 49 patients in group A were treate...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176136/ https://www.ncbi.nlm.nih.gov/pubmed/30344675 http://dx.doi.org/10.3892/etm.2018.6658 |
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author | Xiao, Lin Shu, Fangwu Xu, Cheng Zhang, Zhonggui Huang, Liang Wang, Xianmo Zhang, Yan |
author_facet | Xiao, Lin Shu, Fangwu Xu, Cheng Zhang, Zhonggui Huang, Liang Wang, Xianmo Zhang, Yan |
author_sort | Xiao, Lin |
collection | PubMed |
description | The objective of the present study was to investigate the effect of highly selective peripheral nerve radiofrequency (RF) ablation for the pain caused by severe knee osteoarthritis (OA). A total of 96 patients with knee OA were randomly divided into two groups. The 49 patients in group A were treated with highly selective peripheral nerve RF ablation group and the 47 patients in group B were treated with sodium hyaluronate injection. Visual analogue scale (VAS), Lysholm knee score (LKS), and pain relief before treatment and at 3 days and 3, 6, 9, and 12 months after treatment were compared. At each time point after treatment in group A, both VAS and LKS scores were significantly different compared with before treatment (P<0.05). At 3 days, and at 3 and 6 months after treatment in group B, VAS scores were significantly different from before treatment (P<0.05) and at 9 and 12 months after treatment, the scores were not significantly different from those before treatment. In addition, LKS scores were only significantly different at 3 months after treatment compared with before treatment (P<0.05) and not significantly different after that time point. Furthermore, compared with group B, the rates of effective pain relief in group A were significantly higher at each time point after treatment (P<0.05). Compared with sodium hyaluronate injection, highly selective peripheral nerve RF ablation of the knee was more effective, easy to operate and had no significant adverse effects for the treatment of knee OA. |
format | Online Article Text |
id | pubmed-6176136 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | D.A. Spandidos |
record_format | MEDLINE/PubMed |
spelling | pubmed-61761362018-10-21 Highly selective peripheral nerve radio frequency ablation for the treatment of severe knee osteoarthritis Xiao, Lin Shu, Fangwu Xu, Cheng Zhang, Zhonggui Huang, Liang Wang, Xianmo Zhang, Yan Exp Ther Med Articles The objective of the present study was to investigate the effect of highly selective peripheral nerve radiofrequency (RF) ablation for the pain caused by severe knee osteoarthritis (OA). A total of 96 patients with knee OA were randomly divided into two groups. The 49 patients in group A were treated with highly selective peripheral nerve RF ablation group and the 47 patients in group B were treated with sodium hyaluronate injection. Visual analogue scale (VAS), Lysholm knee score (LKS), and pain relief before treatment and at 3 days and 3, 6, 9, and 12 months after treatment were compared. At each time point after treatment in group A, both VAS and LKS scores were significantly different compared with before treatment (P<0.05). At 3 days, and at 3 and 6 months after treatment in group B, VAS scores were significantly different from before treatment (P<0.05) and at 9 and 12 months after treatment, the scores were not significantly different from those before treatment. In addition, LKS scores were only significantly different at 3 months after treatment compared with before treatment (P<0.05) and not significantly different after that time point. Furthermore, compared with group B, the rates of effective pain relief in group A were significantly higher at each time point after treatment (P<0.05). Compared with sodium hyaluronate injection, highly selective peripheral nerve RF ablation of the knee was more effective, easy to operate and had no significant adverse effects for the treatment of knee OA. D.A. Spandidos 2018-11 2018-08-27 /pmc/articles/PMC6176136/ /pubmed/30344675 http://dx.doi.org/10.3892/etm.2018.6658 Text en Copyright: © Xiao et al. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. |
spellingShingle | Articles Xiao, Lin Shu, Fangwu Xu, Cheng Zhang, Zhonggui Huang, Liang Wang, Xianmo Zhang, Yan Highly selective peripheral nerve radio frequency ablation for the treatment of severe knee osteoarthritis |
title | Highly selective peripheral nerve radio frequency ablation for the treatment of severe knee osteoarthritis |
title_full | Highly selective peripheral nerve radio frequency ablation for the treatment of severe knee osteoarthritis |
title_fullStr | Highly selective peripheral nerve radio frequency ablation for the treatment of severe knee osteoarthritis |
title_full_unstemmed | Highly selective peripheral nerve radio frequency ablation for the treatment of severe knee osteoarthritis |
title_short | Highly selective peripheral nerve radio frequency ablation for the treatment of severe knee osteoarthritis |
title_sort | highly selective peripheral nerve radio frequency ablation for the treatment of severe knee osteoarthritis |
topic | Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176136/ https://www.ncbi.nlm.nih.gov/pubmed/30344675 http://dx.doi.org/10.3892/etm.2018.6658 |
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