Cargando…

Highly selective peripheral nerve radio frequency ablation for the treatment of severe knee osteoarthritis

The objective of the present study was to investigate the effect of highly selective peripheral nerve radiofrequency (RF) ablation for the pain caused by severe knee osteoarthritis (OA). A total of 96 patients with knee OA were randomly divided into two groups. The 49 patients in group A were treate...

Descripción completa

Detalles Bibliográficos
Autores principales: Xiao, Lin, Shu, Fangwu, Xu, Cheng, Zhang, Zhonggui, Huang, Liang, Wang, Xianmo, Zhang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176136/
https://www.ncbi.nlm.nih.gov/pubmed/30344675
http://dx.doi.org/10.3892/etm.2018.6658
_version_ 1783361648158834688
author Xiao, Lin
Shu, Fangwu
Xu, Cheng
Zhang, Zhonggui
Huang, Liang
Wang, Xianmo
Zhang, Yan
author_facet Xiao, Lin
Shu, Fangwu
Xu, Cheng
Zhang, Zhonggui
Huang, Liang
Wang, Xianmo
Zhang, Yan
author_sort Xiao, Lin
collection PubMed
description The objective of the present study was to investigate the effect of highly selective peripheral nerve radiofrequency (RF) ablation for the pain caused by severe knee osteoarthritis (OA). A total of 96 patients with knee OA were randomly divided into two groups. The 49 patients in group A were treated with highly selective peripheral nerve RF ablation group and the 47 patients in group B were treated with sodium hyaluronate injection. Visual analogue scale (VAS), Lysholm knee score (LKS), and pain relief before treatment and at 3 days and 3, 6, 9, and 12 months after treatment were compared. At each time point after treatment in group A, both VAS and LKS scores were significantly different compared with before treatment (P<0.05). At 3 days, and at 3 and 6 months after treatment in group B, VAS scores were significantly different from before treatment (P<0.05) and at 9 and 12 months after treatment, the scores were not significantly different from those before treatment. In addition, LKS scores were only significantly different at 3 months after treatment compared with before treatment (P<0.05) and not significantly different after that time point. Furthermore, compared with group B, the rates of effective pain relief in group A were significantly higher at each time point after treatment (P<0.05). Compared with sodium hyaluronate injection, highly selective peripheral nerve RF ablation of the knee was more effective, easy to operate and had no significant adverse effects for the treatment of knee OA.
format Online
Article
Text
id pubmed-6176136
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher D.A. Spandidos
record_format MEDLINE/PubMed
spelling pubmed-61761362018-10-21 Highly selective peripheral nerve radio frequency ablation for the treatment of severe knee osteoarthritis Xiao, Lin Shu, Fangwu Xu, Cheng Zhang, Zhonggui Huang, Liang Wang, Xianmo Zhang, Yan Exp Ther Med Articles The objective of the present study was to investigate the effect of highly selective peripheral nerve radiofrequency (RF) ablation for the pain caused by severe knee osteoarthritis (OA). A total of 96 patients with knee OA were randomly divided into two groups. The 49 patients in group A were treated with highly selective peripheral nerve RF ablation group and the 47 patients in group B were treated with sodium hyaluronate injection. Visual analogue scale (VAS), Lysholm knee score (LKS), and pain relief before treatment and at 3 days and 3, 6, 9, and 12 months after treatment were compared. At each time point after treatment in group A, both VAS and LKS scores were significantly different compared with before treatment (P<0.05). At 3 days, and at 3 and 6 months after treatment in group B, VAS scores were significantly different from before treatment (P<0.05) and at 9 and 12 months after treatment, the scores were not significantly different from those before treatment. In addition, LKS scores were only significantly different at 3 months after treatment compared with before treatment (P<0.05) and not significantly different after that time point. Furthermore, compared with group B, the rates of effective pain relief in group A were significantly higher at each time point after treatment (P<0.05). Compared with sodium hyaluronate injection, highly selective peripheral nerve RF ablation of the knee was more effective, easy to operate and had no significant adverse effects for the treatment of knee OA. D.A. Spandidos 2018-11 2018-08-27 /pmc/articles/PMC6176136/ /pubmed/30344675 http://dx.doi.org/10.3892/etm.2018.6658 Text en Copyright: © Xiao et al. This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License (https://creativecommons.org/licenses/by-nc-nd/4.0/) , which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.
spellingShingle Articles
Xiao, Lin
Shu, Fangwu
Xu, Cheng
Zhang, Zhonggui
Huang, Liang
Wang, Xianmo
Zhang, Yan
Highly selective peripheral nerve radio frequency ablation for the treatment of severe knee osteoarthritis
title Highly selective peripheral nerve radio frequency ablation for the treatment of severe knee osteoarthritis
title_full Highly selective peripheral nerve radio frequency ablation for the treatment of severe knee osteoarthritis
title_fullStr Highly selective peripheral nerve radio frequency ablation for the treatment of severe knee osteoarthritis
title_full_unstemmed Highly selective peripheral nerve radio frequency ablation for the treatment of severe knee osteoarthritis
title_short Highly selective peripheral nerve radio frequency ablation for the treatment of severe knee osteoarthritis
title_sort highly selective peripheral nerve radio frequency ablation for the treatment of severe knee osteoarthritis
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176136/
https://www.ncbi.nlm.nih.gov/pubmed/30344675
http://dx.doi.org/10.3892/etm.2018.6658
work_keys_str_mv AT xiaolin highlyselectiveperipheralnerveradiofrequencyablationforthetreatmentofseverekneeosteoarthritis
AT shufangwu highlyselectiveperipheralnerveradiofrequencyablationforthetreatmentofseverekneeosteoarthritis
AT xucheng highlyselectiveperipheralnerveradiofrequencyablationforthetreatmentofseverekneeosteoarthritis
AT zhangzhonggui highlyselectiveperipheralnerveradiofrequencyablationforthetreatmentofseverekneeosteoarthritis
AT huangliang highlyselectiveperipheralnerveradiofrequencyablationforthetreatmentofseverekneeosteoarthritis
AT wangxianmo highlyselectiveperipheralnerveradiofrequencyablationforthetreatmentofseverekneeosteoarthritis
AT zhangyan highlyselectiveperipheralnerveradiofrequencyablationforthetreatmentofseverekneeosteoarthritis