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Therapeutic effect of Rho kinase inhibitor FSD-C10 in a mouse model of Alzheimer's disease

Fasudil, a Rho kinase (ROCK) inhibitor, effectively inhibits disease severity in a mouse model of Alzheimer's disease (AD). However, given its significant limitations, including a relatively narrow safety window and poor oral bioavailability, Fasudil is not suitable for long-term use. Thus, scr...

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Detalles Bibliográficos
Autores principales:	Gu, Qing-Fang, Yu, Jie-Zhong, Wu, Hao, Li, Yan-Hua, Liu, Chun-Yun, Feng, Ling, Zhang, Guang-Xian, Xiao, Bao-Guo, Ma, Cun-Gen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2018
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6176147/ https://www.ncbi.nlm.nih.gov/pubmed/30344671 http://dx.doi.org/10.3892/etm.2018.6701

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